|
Symbol Name ID |
Rnf168
ring finger protein 168 MGI:1917488 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Decreased circulating IgA level |
Decreased circulating IgG level |
Decreased circulating total IgM |
Chronic sinusitis |
Recurrent sinusitis |
Generalized lymphadenopathy |
Otitis media |
Pneumonia |
Recurrent pneumonia |
Immunodeficiency |
Recurrent viral infections |
| Disease(s) Associated with RNF168 | |||||||||||
| RIDDLE syndrome |
| Mouse Phenotypes | immune system phenotype |
abnormal thymus morphology |
enlarged thymus |
increased DN3 thymocyte number |
abnormal class switch recombination |
abnormal T cell receptor delta chain V(D)J recombination |
increased double-negative T cell number |
increased eosinophil cell number |
decreased gamma-delta T cell number |
abnormal spleen morphology |
decreased spleen weight |
decreased IgG1 level |
decreased IgG2a level |
decreased IgG3 level |
decreased IgG level |
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| Availability | Mouse Genotype | |||||||||||||||
| Rnf168em1(IMPC)H/Rnf168em1(IMPC)H | ||||||||||||||||
| Rnf168Gt(156B6)Cmhd/Rnf168Gt(156B6)Cmhd | * | |||||||||||||||
| Rnf168Gt(405F11)Cmhd/Rnf168Gt(405F11)Cmhd | * | |||||||||||||||
| Rnf168tm2b(EUCOMM)Hmgu/Rnf168tm2b(EUCOMM)Hmgu | ||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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